PhysiologyProceedings of the National Academy of SciencesPeer-reviewed
Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia
Shavonne L. Teng, Rocco Latorre, Divya Bhansali…·Nigel W. Bunnett
This study shows that targeting protease-activated receptor 2 (PAR2) signaling in organelles using nanomedicines provides sustained analgesia in preclinical models of inflammatory bowel disease.