John Steill

This paper identifies ICAM-1 as a novel hypoimmune target in human pluripotent stem cells, showing that its knock-out reduces immune cell adhesion and enhances graft survival.

This study identifies significant reprogramming of nucleotide metabolism in classically activated macrophages, revealing key regulatory mechanisms and functional consequences.

SKiM discovers and annotates biomedical knowledge using co-occurrence and transformer models to find A-B-C relationships between user-defined concepts.

This study shows that co-differentiating human and mouse pluripotent stem cells accelerates human neural differentiation, with gene expression changes correlating with in utero development.

SKiM is a literature-based discovery system that rediscovered biomedical knowledge and identified potential drug candidates by analyzing PubMed literature.