Joel Lüthi

The paper introduces 3D-4i imaging and analysis to study cell cycle dynamics and transcriptional output during zygotic genome activation in zebrafish embryos.

Shield-4i enables high-throughput, subcellular-resolution imaging of whole-mount structures to study multiscale information flow in multicellular systems.

Fractal introduces a task specification and platform for scalable, reproducible OME-Zarr-native bioimage analysis workflows, demonstrating reproducibility across diverse imaging data and clinical settings.

The paper investigates chromatin dynamics in plant protoplasts during dedifferentiation, finding rapid multiscale changes influenced by nutrients and a decline in chromatin entropy over time.

This paper describes OME-Zarr, a cloud-optimized bioimaging file format developed through community collaboration to improve scalability and data access.

The paper shows astrocytic networks integrate and drive neural activity by influencing inhibitory interneuron firing through calcium signaling and molecular mechanisms.