Ralf P. Richter

This study quantitatively compares the membrane binding and self-assembly of human septin hexamers and octamers using biophysical methods, revealing distinct structural properties and functional implications.

The paper reveals how long-chain heparan sulfate (HS) facilitates paracrine GDNF-GFRα1 signaling by forming a multi-protein complex with RET, essential for signaling in trans but not in cis.

This study shows that varying the number of binding motifs in a disordered protein affects pyrenoid assembly and algal fitness.

This paper introduces two optical sectioning methods for RICM to reduce background noise and improve image quality in complex biological samples.

This paper investigates how PTX3's quaternary structure enables HA crosslinking via interactions with HC1, revealing pH-dependent binding and structural flexibility.

This study shows that Omicron SARS-CoV-2 spike proteins balance heparan sulfate interaction stability and dynamics to enhance mobility in the extracellular matrix, which can be targeted pharmacologically.