Torben W. van Voorst

This study develops a single-step transposon-based method to generate pure GABAergic neurons from iPSCs, showing they mature synaptically and form functional networks.

This study shows tomosyns inhibit synaptic depression by binding to VAMP2-containing template complexes and preventing SNAP-25 association, rather than competing with VAMP2 for SNARE complex assembly.

This study investigates SCN1A mutations in excitatory neuronal networks derived from patient hiPSCs, revealing mutation-specific phenotypes that correlate with clinical outcomes and drug responses.