Inhibition of Stemness Pathways during Acute SIV Limits Infection of Central Memory CD4+ T Cells and Alters Viral Reservoir Activity in Macaques
Riri Rizkianty Hamid, I. Ruiz-Salinas, Nils Schoof…·Maud Mavigner
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Emory UniversityORCID 0000-0003-3075-755XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Riri Rizkianty Hamid, I. Ruiz-Salinas, Nils Schoof…·Maud Mavigner
Michael Kuipa, Abubakarr A. Koroma, I. Leguizamo…·Matthew R. Gardner
This study shows that co-delivering PD-L1 with an AAV-expressed HIV-1 bNAb reduces anti-drug antibodies and improves bNAb expression and protection against HIV in rhesus macaques.
Michael Kuipa, Abubakarr A. Koroma, I. Leguizamo…·Matthew R. Gardner
This study shows that co-delivering PD-L1 with AAV-delivered bNAb 10-1074 reduces ADA responses and improves bNAb durability in rhesus macaques.
Somesh Banerjee, Matthew Ryan Smith, Yining Irene Wang…·Peijian He
The paper identifies mtROS-induced metabolic changes that regulate ferroptosis sensitivity by affecting glutathione and CoQ biosynthesis in hepatocytes and cancer cells.
Johannes B. Goll, Steven E. Bosinger, Travis Lee Jensen…·Daniel Fredric Hoft
This study benchmarks RNA-Seq technical parameters in a clinical vaccine trial to establish guidelines for future studies.