Frank Peske

The paper identifies a novel antibiotic resistance mechanism where fusA mutations slow ribosome movement when aminoglycosides are bound, preventing error cluster formation and maintaining bacterial growth.

This study reveals how GTP hydrolysis by EF-G drives ribosome-tRNA movement through structural changes visualized by cryo-EM.

This study examines how antibiotics affect ribosomal subunit dynamics during translocation, showing varying impacts on SSU movements depending on the antibiotic type.