Anne Cucchiarini

The paper demonstrates the presence of G-quadruplex structures in human blood plasma through experimental validation using synthetic and native nucleic acid samples.

G4All is a curated database of experimentally validated G-quadruplex-forming DNA and RNA sequences with controls, enabling comparative analysis and predictive model development.

This study identifies the NS3 protease domain of Yellow Fever Virus as a high-affinity G4 binder, revealing its interaction mechanism and potential as an antiviral target.

This study identifies and validates G-quadruplex-forming sequences in archaea, demonstrating their presence and function in vivo and identifying potential resolving enzymes.

This study identifies G-quadruplexes as promoter elements that exclude nucleosomes and facilitate RNA polymerase II pausing.