Ho Yan Yeung

This study identifies a new family of hookworm peptides that mimic the chordate gut-brain hormone neurotensin, showing structural and functional similarity to modulate gut function.

The paper identifies prey-specific toxins in cephalopod venom, including neurotensin-mimicking peptides that target fish, revealing an evolutionary strategy for broad venom activity.

This study identifies venom-derived SSTR4 agonists as potential non-opioid therapeutics for peripheral pain conditions.

The paper uses mitochondrial sequencing and venom-gland transcriptomics to study phylogenetic relationships and venom gene diversity in Palauan cone snails.

RAMP3 complexes with GLP-1R at the plasma membrane, shifts signalling toward Ca2+ mobilisation, and enhances insulin secretion in INS-1 832/3 cells; Ramp3 loss blunts GLP-1 responses in mice.

This paper identifies that GLP-1(9-36) inhibits glucagon secretion via the glucagon receptor, while GLP-1(7-36) uses the GLP-1 receptor, revealing distinct mechanisms for glucagon suppression.