Chongguang Chen

This paper introduces engineered mouse models to study the effects of psychedelic drugs by examining HTR2A receptor expression and function.

This study shows that KORs in aPVT neurons mediate morphine withdrawal, anxiety, and fear in both sexes, but only contribute to KOR agonist-induced aversion in males.

This study shows that paternal morphine exposure increases morphine self-administration in male offspring but not females, with region-specific neural changes in reward-related brain areas.

The paper develops a MOR-specific Cre mouse line to study opioid receptor cell types and their molecular characteristics during opioid withdrawal.