Author

Alan V. Smrcka

University of MichiganORCID 0000-0003-3099-8812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:electrophysiology· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Agustin A. RabinoiD· 1 shared Arun AnantharamiD· 1 shared Breanna L. CoffmaniD· 1 shared Brian T. EmmeriD· 1 shared Carole A. ParentiD· 1 shared Chinmay RautiD· 1 shared Daniel AxelrodiD· 1 shared David I. YuleiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

Agustin A. RabinoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 11, 2025

GPR97/ADGRG3 is activated by its tethered peptide agonist and not by steroids to induce neutrophil polarization and migration

Tyler F. Bernadyn, Frank E. Kwarcinski, Naincy R. Chandan…·Gregory G. Tall

1 citation

𝕏 PostBluesky

GeneticsAtherosclerosisPeer-reviewedMar 22, 2025

Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening

Taslima Gani Khan, Juliana Bragazzi Cunha, Chinmay Raut…·Brian T. Emmer

This study uses genome-scale CRISPR screening to identify LDLR and MYLIP as key regulators of Lp(a) uptake in HuH7 cells, with validation in a UK Biobank cohort.

6 citationstop 4%

humanCRISPR screen

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Cell BiologyMolecular Biology of the CellPeer-reviewedMay 17, 2024

A PACAP-activated network for secretion requires coordination of calcium influx and calcium mobilization

Xiaohuan Chen, Nicole A. Bell, Breanna L. Coffman…·Arun Anantharam

The paper shows PACAP induces sustained Ca2+ increases in chromaffin cells by coupling Ca2+ influx and mobilization via PLCε activity.

3 citations

electrophysiologyimaging

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