Valerie Vandenbempt

This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.

The paper constructs a healthy human pancreas reference atlas to contextualize disease states and benchmark models.

The paper constructs a single-cell multiomics atlas of the human pancreas across development, health, and T2D, identifying plastic cell states and lineage trajectories.

The paper uses volumetric imaging and single-cell RNAseq to study human dental pulp responses during tooth decay, identifying cellular mechanisms and progression stages.