Esteban N. Gurzov

This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.

CellCousin2 improves lineage tracing in zebrafish by reducing background recombination and enhancing ablation efficiency with a new system.

This study shows that loss of PTPRK in hepatocytes reduces steatosis and tumour development in obesity-induced hepatocellular carcinoma.

This study shows that cholangiocytes generate new hepatocytes during zebrafish liver regeneration after partial injury during growth.

This study shows that c-Fos in hepatocytes promotes MASLD and HCC by altering metabolic pathways and signaling networks in obesity.

The paper uses volumetric imaging and single-cell RNAseq to study human dental pulp responses during tooth decay, identifying cellular mechanisms and progression stages.