Author

Li Huitong Xie

University of Rochester MedicineORCID 0000-0002-5555-5762Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:multiome· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Amanda A. Pereira· 1 shared Chao ZhangiD· 1 shared Christoph PröscheliD· 1 shared David H. MathewsiD· 1 shared Emiliano P. RicciiD· 1 shared Eng-Soon KhoriD· 1 shared Feng JiangiD· 1 shared Jiang ZhuiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Amanda A. Pereira

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedOct 3, 2023

Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy

Omar M. Hedaya, Kadiam C. Venkata Subbaiah, Feng Jiang…·Peng Yao

The paper identifies dsRNA structures in uORFs that regulate translation and shows ASO targeting can modulate mORF translation and reduce cardiac hypertrophy.

40 citationstop 5%

humanmouse

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedOct 13, 2021

Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs

Yu Huining Sun, Ruoqiao Huiyi Wang, Khai Du…·Xin Zhiguo Li

The paper shows that ribosomes guide piRNA production from mRNAs in 3UTRs after translating upstream long ORFs, revealing a conserved mechanism for piRNA biogenesis.

30 citations

mousemultiple species

𝕏 PostBluesky