Author

Raymond Kooij

Leiden University Medical CenterORCID 0000-0003-3112-704XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ayşegül SapmaziD· 2 shared Paul P. GeurinkiD· 2 shared Vito PoliD· 2 shared Adán Pinto-FernándeziD· 1 shared Benedikt Mathias KessleriD· 1 shared Bjorn R. van DoodewaerdiD· 1 shared Darragh Patrick O'BrieniD· 1 shared Dharjath S. HameediD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

Ayşegül SapmazORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 19, 2025

Huib32: A Potent and Selective USP32 Inhibitor Modulating Endosomal Processes and Advancing Cell-Permeable USP32 Probes

Stephan Scherpe, Vito Pol, Raymond Kooij…·Ayşegül Sapmaz

This paper introduces Huib32, a selective USP32 inhibitor, and two activity-based probes that modulate endosomal processes and provide tools for studying USP32 in cancer and neurodegenerative diseases.

1 citation

proteomicsexperimental assay

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BiochemistrybioRxivPreprintApr 18, 2025

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-specific Protease USP18

Raymond Kooij, Vito Pol, Jin Gan…·Paul P. Geurink

The paper develops a high-throughput synthesis-to-screening method to identify selective USP18 inhibitors from a cyanimide library.

2 citations

experimental assaydrug response / drug discovery

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