Author

Bjorn R. van Doodewaerd

Leiden University Medical CenterORCID 0000-0001-9528-5587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Paul P. GeurinkiD· 3 shared Antonius P. A. JansseniD· 1 shared Ayşegül SapmaziD· 1 shared Bas C. JanseniD· 1 shared Bianca D. M. van ToliD· 1 shared Brenda Arlene SchulmaniD· 1 shared Gerbrand J. van der Heden van NoortiD· 1 shared Guinevere S. M. Lageveen‐KammeijeriD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Paul P. GeurinkORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedAug 27, 2025

High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ1 riboswitch ligands

Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk…·René C. L. Olsthoorn

This paper develops a competitive binding HTS assay to identify small molecule ligands for bacterial PreQ1 riboswitches, discovering 4 hits with activity against multiple riboswitches and one showing translation inhibition.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 22, 2025

Employing neutron-encoded monoUbs to study E2/E3 ligase activity and selectivity for assembling Ub chains

Bianca D. M. van Tol, Bjorn R. van Doodewaerd, Guinevere S. M. Lageveen‐Kammeijer…·Paul P. Geurink

The paper develops a mass spectrometry-based assay to screen E2/E3 ligase pairs for their ability to form ubiquitin chains and analyze chain types.

1 citation

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintApr 18, 2025

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-specific Protease USP18

Raymond Kooij, Vito Pol, Jin Gan…·Paul P. Geurink

The paper develops a high-throughput synthesis-to-screening method to identify selective USP18 inhibitors from a cyanimide library.

2 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky