Developmental BiologybioRxivPreprint
Regulation of FGF/MAPK signaling at the primary cilium base controls the proliferation-neurogenesis balance in human cerebellar organoids
Ludovica Brunetti, Antonia Wiegering, Isabelle Anselme…·Christine Vesque
This study shows that ciliary dysfunction in human cerebellar organoids leads to overactivation of FGF/MAPK signaling, impairing neurogenesis and increasing progenitor proliferation.
DOI 10.1101/2025.04.14.648790