Author

Dingxue Hu

Shenzhen Bay LaboratoryORCID 0000-0003-3137-4331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Changzheng DuiD· 1 shared Jing GaoiD· 1 shared Jingyu YaniD· 1 shared Kun SuniD· 1 shared Mengqi YangiD· 1 shared Qi LiuiD· 1 shared Shiva BasnetiD· 1 shared Shuxia ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Changzheng DuORCID

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1 paper

Recent·Most cited

Proteasome inhibition induces DNA methylation alteration by attenuating the synthesis of DNA methyltransferase 1 and 3B in colorectal cancer

Wenwen Zhou, Yuling Sheng, Dingxue Hu, Yunyun An, Mengqi Yang, Wanqiu Wang, Shiva Basnet, Jingyu Yan, Shuxia Zhang, Qi Liu, Yunze Li, Yi Liang Tan, Jing Gao, Kun Sun, Changzheng Du

This study shows proteasome inhibition alters DNA methylation in colorectal cancer by reducing DNMT1 and DNMT3B synthesis via AKT/mTOR inactivation.

Scientific Reports · Mar 12, 2025Peer-reviewedCancer Biology