Author

Yunyun An

Shenzhen Bay LaboratoryORCID 0000-0001-8662-5535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:DNA methylation· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Kun SuniD· 4 shared Mengqi YangiD· 4 shared Wanqiu WangiD· 4 shared Changzheng DuiD· 3 shared Bianbian Tang· 2 shared Fanglei Gong· 2 shared Huizhen Lin· 2 shared Xiaoyi LiuiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Kun SunORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologyAdvanced SciencePeer-reviewedJan 22, 2026

Cancer-like fragmentomic characteristics of somatic variants in cell-free DNA

Zhenyu Zhang, Yunyun An, Mengqi Yang…·Kun Sun

This study identifies cancer-like fragmentomic traits in somatic variants of cfDNA, enabling cancer diagnosis through integrative genomic and fragmentomic analysis using AI models.

1 citation

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 10, 2025

Cell-free DNA fragmentomic characteristics in transposon elements inform molecular regulators and enhance cancer diagnosis

Fanglei Gong, Yuqi Pan, Huizhen Lin…·Kun Sun

This study identifies cfDNA fragmentomic features in transposon elements as biomarkers for cancer diagnosis, showing improved performance over genome-wide measurements.

DOI 10.1101/2025.07.10.664250

humanmouse

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Cancer BiologybioRxivPreprintMar 30, 2025

Presence of Hepatitis B virus infection in colon cancer

Lishi Li, Wenjing Gong, Yunyun An…·Kun Sun

This study investigates HBV infection in colon cancer patients, finding HBsAg in colonic cells and immune cells, with higher infection rates in tumors.

DOI 10.1101/2025.03.30.646256

humanproteomics

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Cancer BiologyScientific ReportsPeer-reviewedMar 12, 2025

Proteasome inhibition induces DNA methylation alteration by attenuating the synthesis of DNA methyltransferase 1 and 3B in colorectal cancer

Wenwen Zhou, Yuling Sheng, Dingxue Hu…·Changzheng Du

This study shows proteasome inhibition alters DNA methylation in colorectal cancer by reducing DNMT1 and DNMT3B synthesis via AKT/mTOR inactivation.

1 citation

humanDNA methylation

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