Mark D. Adams

TEAL-seq enables sensitive, species-specific gene expression analysis in complex microbial communities using highly multiplexed probes and isothermal amplification.

The paper identifies a novel de novo PAK2 variant in a patient with Knobloch syndrome type 2, supporting PAK2's role in the disorder and expanding its clinical features.

The paper characterizes the CAST/EiJ mouse strain as a model for severe COVID-19 by showing it develops high viral burdens, severe lung pathology, and cytokine dysregulation leading to mortality.