Candice N. Baker

The paper identifies a composite transcriptome signature with high distal heritability that explains 30% of metabolic trait variation across species.

The paper models metabolic disease susceptibility and resilience in genetically diverse mice by analyzing diet-induced metabolic responses across three strains.

The paper characterizes the CAST/EiJ mouse strain as a model for severe COVID-19 by showing it develops high viral burdens, severe lung pathology, and cytokine dysregulation leading to mortality.

Enhlink infers enhancer-promoter linkages using scATAC-seq data and outperforms existing methods, revealing a super-enhancer regulating striatal neuron markers.

The paper identifies metabolic regulation in left-right patterning using spatial transcriptome data, linking glycolysis and Bmp7 to heart and gut looping.