Lindsey M. Crown

Blocking Src-PSD-95 interaction rescues glutamatergic signaling dysregulation in schizophrenia.

This study shows that blocking the Src-PSD-95 interaction with a peptide rescues NMDAR hypofunction and improves behavioral deficits in schizophrenia models.

Immediate and Long-Term Electrophysiological Biomarkers of Antidepressant Behavioral Effects After Subanesthetic Ketamine and Medial Prefrontal Cortex Deep Brain Stimulation Treatment

This study examines electrophysiological biomarkers of antidepressant effects from ketamine and mPFC DBS in rats, finding correlations between specific brain activity patterns and behavioral improvements.

Frequency- and circuit- specific effects of septohippocampal deep brain stimulation in mice as measured by functional ultrasound imaging.

This study uses functional ultrasound imaging to show that septohippocampal DBS at theta frequency increases hippocampal CBV after stimulation offset, unlike high-frequency DBS.