Ryan M. Bastle

The paper identifies ZBTB7A as a key regulator of MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in the orbitofrontal cortex.

This study shows that cocaine exposure increases calreticulin in the ventral hippocampus via ΔFosB, reducing excitability in the vHPC-NAc circuit and promoting cocaine seeking and reward.

The paper identifies dopaminylated proteins in the brain, including γCaMKII, and shows its role in synaptic-to-nuclear signaling and memory formation.

The paper investigates how serotonin modifies histone H3K4me3Q5ser dynamics in the dorsal raphe nucleus under stress and antidepressant exposure, showing its role in gene expression and behavior.

A single enzyme, TGM2, bidirectionally controls H3 monoaminylation dynamics, which, in turn, facilitate neural rhythmicity.