Evolutionary BiologybioRxivPreprint
Experimental evolution of collective β-lactam resistance in Escherichia coli via activation of a dormant outermembrane porin
Abraham Ochoa, Joost Hollander, Rotem Gross…·J. Arjan G. M. de Visser
This study shows that increased collective β-lactam resistance in E. coli arises from activation of a dormant porin, NmpC, through an insertion sequence excision, enhancing drug permeability and filamentation.
DOI 10.64898/2026.08.19.745717