Vassilis Papalazarou

This study identifies SLC25A32 as a critical mitochondrial folate transporter that becomes essential in serine/glycine-starved triple-negative breast cancer, making it a potential therapeutic target.

This study identifies NAD+ limitation and α-ketoglutarate depletion as mechanisms by which pancreatic cancer cells induce muscle atrophy through metabolic rewiring and redox imbalance.

This study shows that dietary serine and glycine restriction delays cancer-associated cachexia in mice by altering host metabolism and reducing inflammation, independent of tumor growth.