Izadora Liranço Furlani

Mitochondrial folate transport becomes essential in serine/glycine-starved triple-negative breast cancer

This study identifies SLC25A32 as a critical mitochondrial folate transporter that becomes essential in serine/glycine-starved triple-negative breast cancer, making it a potential therapeutic target.

NAD+ limitation and α-ketoglutarate depletion define cancer induced muscle atrophy

This study identifies NAD+ limitation and α-ketoglutarate depletion as mechanisms by which pancreatic cancer cells induce muscle atrophy through metabolic rewiring and redox imbalance.

Dietary serine and glycine restriction delays cancer-associated cachexia

This study shows that dietary serine and glycine restriction delays cancer-associated cachexia in mice by altering host metabolism and reducing inflammation, independent of tumor growth.

Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation

This study identifies neutrophil-driven systemic conditioning that links inflammation, tissue regeneration, and metastasis, with UPP1 as a key factor in neutrophil priming.