Author

Xue Gao

Rice UniversityORCID 0000-0003-3213-9704Unclaimed ORCID profile · follow to get notified of new preprints

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Xue Gao1 paper

Biology Disciplines

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Synthetic Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:E. coli· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adam Cusolito· 1 shared Alex DitzeliD· 1 shared Alexander D. Naydich· 1 shared Connie HouiD· 1 shared Dacheng MaiD· 1 shared Elizabeth S. P. Redfield· 1 shared Ella Bedford· 1 shared Fanglong ZhaoiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

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10 top collaborators · 12 mutual co-author links

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1 shared paperSynthetic Biology

Adam Cusolito

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJul 22, 2022

Utilizing a Cell-free Protein Synthesis Platform for Natural Product Synthesis

Alex Ditzel, Fanglong Zhao, Xue Gao, George N. Phillips

The paper demonstrates using a cell-free protein synthesis system to synthesize caffeine in vitro, highlighting its advantages for natural product generation.

DOI 10.1101/2022.07.22.501086

experimental assay

𝕏 PostBluesky

Systems BiologyNature CommunicationsPeer-reviewedJan 25, 2022

Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity

Rongjie Fu, Wei He, Jinzhuang Dou…·Han Xu

This study systematically identifies sequence determinants of CRISPR/Cas9 specificity by analyzing off-target effects of 1,902 gRNAs on 13,314 targets, revealing three key factors and developing a predictive tool.

55 citationstop 5%

CRISPR screenstatistical model

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Synthetic BiologyCell ReportsPeer-reviewedMar 1, 2020

Synthetic cassettes for pH-mediated sensing, counting and containment

Finn Stirling, Alexander D. Naydich, Juliet Tongue Bramante…·Pamela A. Silver

The paper develops a pH-sensitive kill switch and pulse-counting circuit for bacterial containment and sensing.

67 citations

E. coliexperimental assay

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