Author

Yujie Dong

Yunnan UniversityORCID 0000-0003-3246-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

François Paquet‐DurandiD· 3 shared Jie YaniD· 3 shared Kangwei JiaoiD· 3 shared Lan WangiD· 3 shared Qianlu YangiD· 2 shared Qianxi YangiD· 2 shared Zhulin HuiD· 2 shared Christina Schwarz· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

François Paquet‐DurandORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 7, 2025

Resolving the estrogen paradox in hereditary retinal degeneration: Esr1 activation suppresses Tnf-α signaling as a photoreceptor self-protection mechanism

Yuting Li, Yadi Li, Jiarui Luo…·Jie Yan

This study identifies Esr1 activation as a protective mechanism against neuroinflammation in retinal degeneration, showing it suppresses Tnf-α signaling and reduces photoreceptor death.

DOI 10.1101/2025.09.07.674682

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceCell Communication and SignalingPeer-reviewedFeb 1, 2024

Inherited retinal degeneration: T-type voltage-gated channels, Na+/Ca2+-exchanger, and calpain-2 promote photoreceptor cell death.

Jie Yan, Lan Wang, Qianlu Yang…·François Paquet‐Durand

This study investigates the role of calcium signaling in photoreceptor cell death in IRD using mouse models and identifies calpain-2 as a key contributor to degeneration.

22 citations

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsInternational Journal of Molecular SciencesPeer-reviewedOct 12, 2022

Single-cell transcriptomic profiling in inherited retinal degen-eration reveals distinct metabolic pathways in rod and cone photoreceptors

Yiyi Chen, Yujie Dong, Jie Yan…·François Paquet‐Durand

This study uses scRNA-seq to analyze metabolic changes in mouse retinal cells during degeneration, identifying Ca2+-signaling and MAPK pathway involvement.

21 citations

mousescRNA-seq

𝕏 PostBluesky