Cancer BiologybioRxivPreprint
Highly plastic macrophage niches orchestrate acquired quiescence and reactivation in breast-cancer bone metastasis
Yasuto Takeuchi, Huazi Zhang, Takahiko Murayama…·Noriko Gotoh
The paper identifies CXCL16 macrophages in bone metastases that transiently restrain cancer growth and G-CSF niches that promote reactivation, revealing CAF-bone-marrow interactions as a therapeutic target.
DOI 10.64898/2026.08.31.748298