Ginés Morata

This study shows that Dpp and immune response factors mediate paracrine induction of senescent cells in Drosophila, increasing the proportion of senescent cells from 10% to 24%.

This study identifies Hipk as a regulator of Dronc stability and apoptotic signaling in Drosophila, revealing a feedback loop between Hipk and Dronc.

The paper investigates size compensation in Drosophila wing imaginal discs after ionizing radiation, finding that it occurs without increased proliferation or reliance on JNK, JAK/STAT, or Wg pathways.

This study shows that lack of apoptosis in Drosophila epithelial cells leads to senescence and tumorigenesis, with tumorigenic potential depending on cell identity and JNK pathway activation.