Carlos Estella

This study identifies three distinct mechanisms by which Xrp1 is induced in response to different stresses in Drosophila, highlighting its role in the Integrated Stress Response.

The paper identifies a signaling network motif where dimerization-linked nucleocytoplasmic shuttling couples protein expression levels with intracellular localization, modulating signaling cascade activity.

This study identifies bru1 as a critical regulator of the mitotic-to-meiotic transition in Drosophila female germline cells, showing its role in preventing DNA damage and apoptosis during gametogenesis.

This study investigates the temporal dynamics of apoptosis-induced proliferation in Drosophila pupal wings, revealing that this regenerative response declines after 35 hours APF due to ecdysone-responsive gene activity.

This study shows that cell proliferation and Notch signaling work together to create epithelial folds in Drosophila leg development through mechanical forces and cell shape changes.

This study shows that lack of apoptosis in Drosophila epithelial cells leads to senescence and tumorigenesis, with tumorigenic potential depending on cell identity and JNK pathway activation.

The paper shows that Dpp and Hedgehog signaling pathways drive glial cell proliferation and migration in response to neuronal damage in Drosophila eye discs.

This study shows that Drosophila p53 pro-apoptotic activity is regulated by Cdk1, linking cell cycle status to DNA damage response.

The paper investigates the in vivo function of the conserved BTD-box domain in Drosophila Sp1 and btd during development, finding it is not essential for viability but plays a role in gene regulation and limb identity.