Author

Shrenik C. Mehta

GenentechORCID 0000-0003-3302-7069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1

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Alavattam SreedharaiD· 1 shared Andrew M. WatkinsiD· 1 shared Bob Kelley· 1 shared Caleigh M. AzumayaiD· 1 shared Cecilia ChiuiD· 1 shared Flaviyan Jerome IrudayanathaniD· 1 shared Franziska SeegeriD· 1 shared Jonathan Zarzar· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alavattam SreedharaORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 29, 2025

Rational design of oxidation-resistant antibodies through local electrostatic modulation

Sunidhi Lenka, Shrenik C. Mehta, Nicole M. Stephens…·Saeed Izadi

This paper develops a machine learning model to predict Trp oxidation risk in antibodies and shows that modulating electrostatic potential reduces oxidation while maintaining binding affinity.

DOI 10.1101/2025.06.29.662139

protein structuremachine learning (classical)

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