Author
University of Eastern FinlandORCID 0000-0003-3308-8662Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Cindy David Sarmento, Gabin Drouard, Toni Tapani Saari…·Eero Vuoksimaa
This study explores proteomic and epigenetic aging clocks as biomarkers for Alzheimer's disease phenotypes, finding proteomic clocks improve explained variance in cognitive and biomarker measures by up to 18%.
Hamilton Se‐Hwee Oh, Deniz Yagmur Urey, Linda Karlsson…·Tony Wyss‐Coray
CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).
Valtteri Julkunen, Claudia Schwarz, Juho Kalapudas…·Zhihao Ding
The paper demonstrates the feasibility of conducting clinical recall studies from the FinnGen biobank to collect customized clinical data from participants with Alzheimer's disease or mild cognitive disorder.
Vahid Gazestani, Tushar Kamath, Naeem M. Nadaf…·Evan Z. Macosko
The paper identifies a transient hyperactive neuronal state in early Alzheimer's disease using single-nucleus transcriptomics from living patients.
Rosa Woldegebriel, Jouni Kvist, Matthew A. White…·Henna Tyynismaa
This study shows that GANP deficiency in human motor neurons disrupts gene regulation and RNA metabolism, affecting nearly 40% of expressed genes and splicing patterns.