Author

Gunther Wennemuth

University of Duisburg-EssenORCID 0000-0003-3313-2475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Caroline WiesehöferiD· 2 shared Jean‐Ju ChungiD· 2 shared Adrian Tibor PressiD· 1 shared Alex J. McCarthyiD· 1 shared Aura Stoskus· 1 shared Bernhard B. SingeriD· 1 shared Cameron C. GardneriD· 1 shared Irina Kube‐GoloviniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Caroline WiesehöferORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 20, 2026

Soluble ZP2 N-terminal fragments activate CatSper-dependent Ca2+ entry and regulate motility and acrosomal exocytosis in mammalian sperm

Caroline Wiesehöfer, Lorena Sunjic, Lara Suetin…·Gunther Wennemuth

This study identifies soluble ZP2 N-terminal fragments as activators of CatSper-dependent Ca2+ entry, regulating sperm motility and acrosomal exocytosis in mice and humans.

DOI 10.64898/2026.08.19.745727

mousehuman

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Cell BiologybioRxivPreprintOct 13, 2025

Coordinated CAII and CAIV establish a dual pH-regulatory axis essential for CatSper activation during sperm maturation and capacitation

Caroline Wiesehöfer, Cameron C. Gardner, Aura Stoskus…·Jean‐Ju Chung

This study shows that coordinated CAII and CAIV pH regulation is essential for sperm motility by establishing dual-compartment pH environments that activate CatSper channels.

DOI 10.1101/2025.10.13.681600

mouseexperimental assay

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ImmunologybioRxivPreprintMar 16, 2025

LILRA5 functions to induce ROS production on innate immune cells

Zuyi Fu, Matevž Rumpret, Irina Kube‐Golovin…·Alex J. McCarthy

This study identifies LILRA5 as an activating receptor on phagocytes that stimulates ROS production and shows its dynamic regulation in response to infection and inflammation.

DOI 10.1101/2025.03.16.643524

humanproteomics

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