Author

Akshay Joshi

University College LondonORCID 0000-0003-3320-8740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christos GeorgiadisiD· 2 shared Oliver GoughiD· 2 shared Renuka KadirkamanathaniD· 2 shared Roland PreeceiD· 2 shared Waseem QasimiD· 2 shared Annie EtukiD· 1 shared Arnold KloosiD· 1 shared Axel SchambachiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Christos GeorgiadisORCID

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2 papers

Recent·Most cited

ImmunologyHaematologicaPeer-reviewedDec 24, 2025

Allo-defensive, multiplex base-edited, anti-CD38 CAR T cells for "off-the-shelf" Immunotherapy

Roland Preece, Oliver Gough, Akshay Joshi…·Waseem Qasim

This paper develops base-edited CAR T cells targeting CD38 to create an off-the-shelf immunotherapy that avoids allo-rejection and shows anti-leukemic activity.

1 citation

humanCRISPR screen

𝕏 PostBluesky

ImmunologyLeukemiaPeer-reviewedOct 1, 2025

Base edited "universal" donor CAR T cell strategies for acute myeloid leukaemia

Renuka Kadirkamanathan, Christos Georgiadis, Arnold Kloos…·Waseem Qasim

This study shows that base edited universal donor CAR T cells targeting multiple antigens can inhibit AML in mice, with combination therapies needed for heterogeneous disease.

8 citations

mouseCITE-seq

𝕏 PostBluesky