Zoltán Molnár

High-throughput light-sheet 3D microscopy of whole rodent brain microstructure for integration with MRI

The paper integrates 3D light-sheet microscopy with diffusion MRI to predict cellular features from MRI data across multiple mouse strains.

Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep

This study shows that silencing layer 6b neurons in mice alters theta frequency and EEG power during wake and sleep, and reduces orexin-induced wakefulness.

Distinct representations of economic variables across regions and projections of the frontal cortex

The paper identifies distinct spatial and projection-based encoding of economic variables in the frontal cortex of mice during decision-making tasks.

An anthropoid/strepsirrhine divergence in ventral visual stream connectivity

This study compares white matter connectivity in two anthropoids and one strepsirrhine using diffusion MRI, finding greater dorsal prefrontal innervation in anthropoids.

Contrasting effects of global and local cortical activity on the regulation of sleep

This study investigates how global and local cortical activity affects sleep regulation using chemogenetic manipulations of Rbp4-Cre+ neurons.

An orexin-sensitive subpopulation of layer 6 neurons regulates cortical excitability and anxiety behaviour.

The paper identifies orexin-sensitive layer 6 neurons in the prefrontal cortex that regulate cortical excitability and anxiety behaviour.

Chronic abolition of evoked vesicle release from layer 5 projection neurons disrupts the laminar distribution of parvalbumin interneurons in the adult cortex

This study shows that chronic disruption of vesicle release from layer 5 pyramidal neurons affects the laminar distribution of parvalbumin interneurons in the adult cortex but not their density or developmental trajectory.

Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

This study shows that clozapine-N-oxide and compound 21 affect sleep in mice, suggesting that chemogenetic actuators may have off-target effects beyond DREADD receptor activation.

Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

This study shows ZIKV alters metabolism in different fetal neuronal progenitors, potentially affecting neurodevelopment during early pregnancy.

Temporal origin of mouse claustrum and development of its cortical projections

This study determines the developmental timeline of the mouse claustrum, including neuronal birthdates, spatial localization, and the maturation of its cortical projections.

A role for the cortex in sleep-wake regulation

This study shows that silencing specific cortical neurons in mice increases wakefulness and reduces sleep rebound after deprivation, highlighting the cortex's role in sleep regulation.

Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal somatosensory cortex

The paper investigates the synaptic connectivity of Lpar1-EGFP subplate neurons in mouse somatosensory cortex, identifying two subtypes with distinct axonal projections and input patterns.

Maturation of complex synaptic connections of layer 5 cortical axons in the posterior thalamic nucleus requires SNAP25

This study shows that SNAP25 is required for the maturation of complex synaptic connections in layer 5 cortical axons in the posterior thalamic nucleus, but not for their initial formation.

Ontogeny of the VIP+ interneuron sensory-motor circuit prior to active whisking

The paper examines the development of VIP+ interneuron circuits in mouse somatosensory cortex, revealing distinct input and output connections and the role of Prox1 in local connectivity.

Mathematical modelling of cortical neurogenesis reveals that the founder population does not necessarily scale with neuronal output

The paper develops a mathematical model of cortical neurogenesis to show that neuronal output can increase without a proportional increase in the founder population size.