Author

Takeshi Isoda

University of California San DiegoORCID 0000-0003-3349-3705Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Cornelis MurreiD· 1 shared Hanbin Lu· 1 shared Matthew Denholtz· 1 shared Simon Döhrmann· 1 shared Victor NizetiD· 1 shared Yina ZhuiD· 1 shared Zhaoren HeiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Cornelis MurreORCID

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1 paper

Recent·Most cited

GenomicsGenes & DevelopmentPeer-reviewedFeb 1, 2020

Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program

Matthew Denholtz, Yina Zhu, Zhaoren He…·Cornelis Murre

This study shows that human neutrophils reposition inflammatory genes to a transcriptionally permissive compartment within hours of microbial exposure, enabling rapid transcriptional responses.

39 citations

humanbulk RNA-seq

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