Author

Simon Döhrmann

Cidara Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alain NoncovichiD· 1 shared Allen Borchardt· 1 shared Amanda L. Almaguer· 1 shared Cornelis MurreiD· 1 shared Daniel C. Bensen· 1 shared Douglas E. Zuill· 1 shared Elizabeth Abelovski· 1 shared Grayson HoughiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Alain NoncovichORCID

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2 papers

Recent·Most cited

CD388: A universally protective Drug-Fc Conjugate that targets influenza virus neuraminidase

Simon Döhrmann, James M Levin, Jason N. Cole, Allen Borchardt, Karin Amundson, Amanda L. Almaguer, Elizabeth Abelovski, Rajvir Grewal, Douglas E. Zuill, Nicholas Dedeic, Grayson Hough, Joanne Fortier, Joanna L. Donatelli, Thanh Lam, Zhiyong Chen, , Leslie W. Tari

This paper describes CD388, a drug-Fc conjugate that targets influenza virus neuraminidase, showing universal antiviral activity across multiple strains and demonstrating efficacy in mouse models.

Nature Microbiology · Mar 17, 2025Peer-reviewedMicrobiology

Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program

Matthew Denholtz, Yina Zhu, Zhaoren He, Hanbin Lu, Takeshi Isoda, Simon Döhrmann, Victor Nizet, Cornelis Murre

This study shows that human neutrophils reposition inflammatory genes to a transcriptionally permissive compartment within hours of microbial exposure, enabling rapid transcriptional responses.

Genes & Development · Feb 1, 2020Peer-reviewedGenomics