Rolf Sprengel

This study shows that GluA1 dysfunction leads to impaired short-term habituation, resulting in a hyper-dopaminergic phenotype in the nucleus accumbens, which may contribute to aberrant salience in schizophrenia.

The paper investigates how neuronal stimulation leads to astrocytic Ca2+ elevation through membrane permeability and IP3R2-dependent Ca2+-induced Ca2+ release at mouse hippocampal synapses.

This study identifies sleep-wake specific astrocytic Ca2+ signaling and its role in modulating sleep transitions and stability.

RetroLEAP enables retrograde trans-synaptic labeling, expression, and perturbation of neurons using a GFP-dependent recombinase system.