Cell BiologybioRxivPreprint
Clonal hematopoiesis-associated DNMT3A mutations derepress bivalent Polycomb target genes and enhance macrophage migration
DOI 10.64898/2026.09.24.754138
Author
Ivan Marazzi
University of California, IrvineORCID 0000-0003-3376-0922Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 24 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
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The competition between splicing and 3' processing shapes the human transcriptome
Lindsey V. Soles, Shuangyu Li, Liang Liu…·Yongsheng Shi
The paper shows that splicing and 3' processing compete to shape the human transcriptome, with splicing inhibition activating 3' processing and vice versa.
4 citations - Systems BiologybioRxivPreprint
Gene regulatory networks define human airway epithelial cell types and their distinct responses to type I interferon
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Convergent DNA Methylation Abnormalities at Bivalent Chromatin in Human Growth Disorders
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This study identifies locus-specific DNA methylation defects at bivalent chromatin as a common feature in growth disorders caused by DNMT3A or NSD1 mutations.
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The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery
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HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness
Jessica Ho, Federico Di Tullio, Megan Catherine Schwarz…·Ernesto Guccione
This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.
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