Author

Ian M. Cartwright

Veterans Health AdministrationORCID 0000-0003-3430-0143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Geetha BhagavatulaiD· 3 shared Sean P. ColganiD· 3 shared Alexander S. DowdelliD· 2 shared Calen A. SteineriD· 2 shared Caroline H. T. HalliD· 2 shared Faiz Minhajuddin· 2 shared Jacob A. CountessiD· 2 shared Joseph C. OnyiahiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Geetha BhagavatulaORCID

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3 papers

Recent·Most cited

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedApr 9, 2026

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa

Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim…·Sean P. Colgan

This study identifies a butyrate analog, 3-chlorobutyrate, that enhances epithelial barrier formation and is protective in colitis without affecting intestinal stem cells.

3 citationstop 3%

mousebulk RNA-seq

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Cancer BiologyJCI InsightPeer-reviewedDec 17, 2025

Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner

Rosemary C. Callahan, Jillian Curry, Geetha Bhagavatula…·Joseph C. Onyiah

This study shows that epithelial HO-1 promotes colonic tumorigenesis in chronic inflammation by increasing iron availability and oxidative stress, while protecting against acute heme toxicity.

5 citations

mousescRNA-seq

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Cell BiologybioRxivPreprintMay 14, 2025

Regulation of Epithelial HIF by Probiotic Escherichia coli

Alexander S. Dowdell, Rebecca L. Roer, Geetha Bhagavatula…·Sean P. Colgan

This study shows that probiotic E. coli stabilizes HIF in intestinal epithelial cells, promoting a pro-barrier transcriptional program through aerobic respiration, and induces tissue hypoxia in vivo.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky