Author

Caroline H. T. Hall

Children's Hospital ColoradoORCID 0000-0002-7100-3423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Faiz Minhajuddin· 2 shared Geetha BhagavatulaiD· 2 shared Ian M. CartwrightiD· 2 shared Joseph C. OnyiahiD· 2 shared Sean P. ColganiD· 2 shared Alexander S. DowdelliD· 1 shared Alfredo OrnelasiD· 1 shared Alyse W. StaleyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Faiz Minhajuddin

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa

Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim, Rachel H. Cohen, Brittany Gomez, Rebecca L. Roer, Faiz Minhajuddin, Kiranmayee Yenugudhati Vijaya Sai, Liheng Zhou, Julia L.M. Dunn, Caleb Chandler, Philip Reigan, Ian M. Cartwright, Caroline H. T. Hall, Geetha Bhagavatula, , Sean P. Colgan

This study identifies a butyrate analog, 3-chlorobutyrate, that enhances epithelial barrier formation and is protective in colitis without affecting intestinal stem cells.

Proceedings of the National Academy of Sciences · Apr 9, 2026Peer-reviewedMolecular Biology

Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner

Rosemary C. Callahan, Jillian Curry, Geetha Bhagavatula, Alyse W. Staley, Rachel E.M. Schaefer, Faiz Minhajuddin, Liheng Zhou, Rane M. Neuhart, Shaikh Muhammad Atif, David J. Orlicky, Ian M. Cartwright, Mark E. Gerich, Calen A. Steiner, Arianne L. Theiss, Caroline H. T. Hall, , Joseph C. Onyiah

This study shows that epithelial HO-1 promotes colonic tumorigenesis in chronic inflammation by increasing iron availability and oxidative stress, while protecting against acute heme toxicity.

JCI Insight · Dec 17, 2025Peer-reviewedCancer Biology