Stephen Mbigha Ghogomu

This paper designs a chimeric vaccine against Necator americanus using immunoinformatics, combining epitopes from three antigens with an adjuvant to elicit immune responses and ensure safety.

This paper retrospectively evaluates the safety and immunogenicity of three hookworm vaccine candidates using immunoinformatics, identifying Na-APR-1 as the most promising with broad epitope coverage and favorable TLR4 interactions.

This paper designs and computationally validates two novel multiepitope antigens for Mpox serosurveillance using immunoinformatic approaches and structural analysis.

This study evaluates the safety and immunogenicity of a novel onchocerciasis vaccine candidate, OvMANE1, in mice, showing increased antibody levels and cellular immune responses.

This study investigates whether Onchocerca ochengi infection contributes to epilepsy development using a gerbil model, finding significant physical effects but no behavioral evidence of epilepsy.

The paper predicts the immunogenicity and safety of two vaccine candidates against onchocerciasis using immunoinformatics, identifying their potential to induce protective immune responses.

This study identifies two mutations in CYP6P4a and CYP6P4b genes driving pyrethroid resistance in Anopheles funestus and develops DNA-based assays to detect these mutations in West Africa.