Charles Sinclair Wondji

The paper investigates how environmental pollutants like PAHs affect insecticide resistance in malaria vectors through multi-generational selection experiments and transcriptomic analysis.

This study characterizes a new Anopheles funestus colony (FUTAZ) established in Tanzania, comparing its fitness traits and genetic markers to wild and existing colonies.

This study establishes and validates discriminating concentrations for broflanilide and isocycloseram in mosquito species to monitor insecticide resistance.

This study compares insecticide susceptibility of Kisumu mosquito colonies across 16 facilities, finding significant variability in susceptibility to different insecticides.

This study identifies metabolomic changes in permethrin-resistant Anopheles gambiae mosquitoes from Cameroon, revealing metabolic and detoxification pathways contributing to resistance.

This study identifies differentially expressed genes in Anopheles gambiae mosquitoes infected with Plasmodium ovale, highlighting potential targets for transmission-blocking strategies.

This study identifies CYP6Z genes in An. gambiae as drivers of broad-spectrum insecticide resistance through transcriptional upregulation and functional validation.

The paper analyzes genomic diversity in Anopheles funestus across Africa, identifying genetic variation, adaptation signals, and conservation of a gene drive target.

In Tororo, Uganda, An. funestus tolerated clothianidin-sprayed walls better than An. gambiae yet was killed on pirimiphos-methyl walls up to 7 months post-spray, implicating it in the malaria resurgence.

This study identifies a QTL and associated polymorphisms conferring resistance to alpha-cypermethrin in Anopheles funestus using genetic crosses and BSA mapping.

This study quantifies Asaia sp. infection in Anopheles mosquitoes from Cameroon and finds no correlation between Asaia and Plasmodium falciparum infection.

This study identifies a single mutation G454A in CYP9K1 as a driver of pyrethroid resistance in Anopheles funestus, reducing bed net efficacy and highlighting the need for resistance monitoring.

This study identifies two mutations in CYP6P4a and CYP6P4b genes driving pyrethroid resistance in Anopheles funestus and develops DNA-based assays to detect these mutations in West Africa.

This study identifies the E205D mutation in CYP6P3 as a driver of pyrethroid resistance in Anopheles gambiae, showing its association with resistance and its interaction with kdr mutations.

The paper identifies overexpression and nonsynonymous mutations in UGT genes associated with pyrethroid resistance in Anopheles funestus using GWAS-PoolSeq and transcriptomic analysis.

This study identifies a CYP9K1 haplotype associated with pyrethroid resistance in Anopheles funestus using multi-omics analysis and functional validation.

The paper identifies molecular drivers of insecticide resistance in Anopheles coluzzii populations across the Sahel region, highlighting key genes and chromosomal inversions associated with resistance to pyrethroids and other insecticides.

The paper analyzes genetic resistance markers in Plasmodium falciparum from malaria vectors in Cameroon to assess artemisinin and partner drug resistance.

This paper describes an optimized CRISPR-based system for transgene insertion in Anopheles funestus, enabling efficient homology-directed repair for genetic modifications.

This study investigates how metabolic resistance genes affect blood feeding in Anopheles funestus, finding that CYP6P9a resistance increases blood feeding success and meal size.