Molecular BiologyNature CommunicationsPeer-reviewed
Loss of Cohesin regulator PDS5A reveals repressive role of Polycomb loops
Daniel Bsteh, Hagar F. Moussa, Georg Michlits…·Oliver Bell
The paper identifies PDS5A as a cohesin regulator linking Polycomb silencing and 3D genome organization, showing that its loss disrupts cohesin activity and Polycomb loops without affecting repressive chromatin marks.