Ramesh Yelagandula

This study identifies HIPK2 and IKKβ as kinases that phosphorylate TAp63α, stabilizing it during the oocyte DNA damage response and enhancing oocyte survival.

This study identifies ZNF462 as an epigenetic repressor that controls opposing developmental tempos in human neural and cranial neural crest lineages by regulating lineage-specific enhancers.

The paper catalogs mobile element insertions in 82 Indian populations, revealing population-specific variants not present in European databases and highlighting their potential impact on disease associations.

ORFtag enables proteome-scale tagging and functional screening in mammalian cells, identifying known and novel regulators of transcription and post-transcriptional processes.

The paper identifies PDS5A as a cohesin regulator linking Polycomb silencing and 3D genome organization, showing that its loss disrupts cohesin activity and Polycomb loops without affecting repressive chromatin marks.

The paper investigates how histone variants, particularly H2A variants, influence chromatin states in Arabidopsis thaliana by examining their interactions with chromatin remodelers like DDM1.

The paper identifies chromatin landscapes in Arabidopsis that regulate transcriptional activity, showing that histone variants and modifications define these landscapes rather than the reverse.

The paper shows that H2A.W and H3K9me work together with H1 and CH methylation to silence transposons in Arabidopsis.

This study identifies ZFP462's role in restricting endodermal gene expression by targeting transposon-derived enhancers and modulating histone methylation in mouse embryonic stem cells.

This study shows that H2A.W and H1 co-regulate heterochromatin accessibility and DNA methylation in flowering plants by modulating H1 deposition and non-CG methylation.