Marcela L. Moreira

The paper investigates how immune responses to infection affect peripheral sympathetic neuron functions, finding that cytokines and interferons alter nerve growth and neuron excitability.

Single-cell RNA and BCR sequencing of infected mouse spleens shows class switching overlaps clonal expansion, GC-seeding clones also form plasmablasts, and SHM proceeds at constant rate.

This study distinguishes tissue-resident memory (TRM) and exhausted T (TEX) cells in tumors by analyzing their antigen reactivity, clonality, and functional outcomes.