Author

Yanquan Zhang

University of KentuckyORCID 0000-0003-3527-9972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chaohao LiiD· 2 shared Derek B. AllisoniD· 2 shared Jia PengiD· 2 shared Qing ShaoiD· 2 shared Ruixin WangiD· 2 shared Xinyi WangiD· 2 shared Xiongjian RaoiD· 2 shared Zhiguo LiiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Chaohao LiORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 27, 2026

PLK1-mediated phosphorylation of PHGDH reprograms serine metabolism in advanced prostate cancer

Xiongjian Rao, Derek B. Allison, Robert M Flight…·Xiaoqi Liu

The paper identifies PLK1-mediated phosphorylation of PHGDH as a mechanism driving serine metabolism reprogramming in advanced prostate cancer, increasing reliance on exogenous serine uptake.

2 citations

humanmetabolomics

𝕏 PostBluesky

Cancer BiologyJournal of Biological ChemistryPeer-reviewedJun 20, 2025

Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

Qiongsi Zhang, Jia Peng, Zhiguo Li…·Xiaoqi Liu

This study shows that PLK1-mediated PDHA1 phosphorylation impairs mitochondrial function and promotes Cr(VI)-induced lung cancer progression by disrupting energy metabolism and apoptosis.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky