Author

Zhiguo Li

University of KentuckyORCID 0000-0002-6869-2766Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhiguo Li1 paper · Xijing Hospital

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Derek B. AllisoniD· 3 shared Jia PengiD· 3 shared Xiongjian RaoiD· 3 shared Chaohao LiiD· 2 shared Chi WangiD· 2 shared Daheng HeiD· 2 shared Ka-wing FongiD· 2 shared Qing ShaoiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Derek B. AllisonORCID

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3 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 27, 2026

PLK1-mediated phosphorylation of PHGDH reprograms serine metabolism in advanced prostate cancer

Xiongjian Rao, Derek B. Allison, Robert M Flight…·Xiaoqi Liu

The paper identifies PLK1-mediated phosphorylation of PHGDH as a mechanism driving serine metabolism reprogramming in advanced prostate cancer, increasing reliance on exogenous serine uptake.

2 citations

humanmetabolomics

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ImmunologyMolecular and Cellular BiologyPeer-reviewedJun 5, 2026

mTORC1-Dependent Regulation of the CCL24-CCR3 Axis Controls Granuloma Formation and Maintenance in Sarcoidosis

Xiongjian Rao, Jinpeng Liu, Derek B. Allison…·Xiaoqi Liu

This study identifies mTORC1's role in regulating the CCL24-CCR3 axis, showing its impact on granuloma formation and maintenance in sarcoidosis, with therapeutic implications.

DOI 10.1080/10985549.2026.2680144

mouseexperimental assay

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Cancer BiologyJournal of Biological ChemistryPeer-reviewedJun 20, 2025

Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

Qiongsi Zhang, Jia Peng, Zhiguo Li…·Xiaoqi Liu

This study shows that PLK1-mediated PDHA1 phosphorylation impairs mitochondrial function and promotes Cr(VI)-induced lung cancer progression by disrupting energy metabolism and apoptosis.

6 citations

humanbulk RNA-seq

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