Simon Walker‐Samuel

Quantitative Susceptibility Mapping for Differentiating Hydroxyapatite and Calcium Oxalate Breast Calcifications at 3T: A Phantom Study

This paper evaluates quantitative susceptibility mapping (QSM) to differentiate hydroxyapatite and calcium oxalate breast calcifications in phantoms, showing QSM detects HA while R2* elevates at both types.

Mechanisms of macular oedema development and therapeutic response: An in-silico modelling study

This study uses a computational model to explore how Muller cell orientation affects oedema and treatment response in Diabetic Macular Oedema.

Real time evaluation of the liver microcirculation by whole organ machine perfusion within an MRI system

This study demonstrates the use of MRI to evaluate liver microcirculation during machine perfusion, showing improved preservation and quantitative vascular analysis.

Tube2FEM: a general-purpose highly-automated pipeline for flow related processes in (embedded) tubular objects

This paper introduces a highly-automated pipeline for generating simulation-ready meshes of tubular structures, enabling CFD simulations across various biomedical and industrial applications.

Examination of the role of mutualism in immune evasion

This study uses a computational simulation to show that mutualism enhances immune evasion in slow-growing tumors, increasing their survival chances compared to tumors without mutualism.

Development of noninvasive biomarkers of response to proteasome inhibitor therapy (ixazomib) by imaging disrupted protein homeostasis in mouse models of solid tumors

This study uses CEST MRI to noninvasively monitor proteasome inhibitor response in mouse tumor models, showing increased CEST signals with higher drug doses and varying tumor sensitivity.

Non-invasive measurement of hepatic venous oxygen saturation (ShvO2) with quantitative susceptibility mapping in normal mouse liver and livers bearing colorectal metastases

This study uses quantitative susceptibility mapping (QSM) to non-invasively measure hepatic venous oxygen saturation in mice, showing significant differences in oxygen levels between healthy livers and those with colorectal metastases.

Deep learning diffusion fingerprinting to detect brain tumour response to chemotherapy

This paper introduces DLDF, a deep learning method that detects brain tumor response to chemotherapy using diffusion-weighted MRI in a mouse model, showing it can segment tumors, distinguish tumor age, and detect chemotherapy effects with limited data.

Quantitation of brain tumour microstructure response to Temozolomide therapy using non-invasive VERDICT MRI

This study evaluates VERDICT MRI for detecting early response to Temozolomide therapy in brain tumours, showing it is more sensitive than structural or ADC measurements.